March 31, 2012

Under Consideration


It’s 2:38am.  My heart is heavy and I can’t sleep.  So rather than just lie there, I decided to ask for prayer and spend some time in the Word. 

I let a few know this past afternoon that my transplant team contacted M-47.  He said that he would "take it under consideration."  :/  While I understand that this is a big commitment on his part, it was discouraging to hear that these considerations had not already been made.  He is tentatively scheduled for an information session next Tuesday, April 3, and a physical exam April 4, contingent on his answer on the 3rd.  Please pray that God would touch his heart and mind toward this gift. 

I also have several unspoken requests.  He knows.  I ask you to kneel with me to leave them at His feet.

Do not let your hearts be troubled. Trust in God; trust also in me.
John 14:1

Peace I leave with you; my peace I give you.  I do not give to you as the world gives.
Do not let your hearts be troubled and do not be afraid.”
John 14:27

The LORD is my rock, my fortress, and my deliverer; my God, my strength, 
in whom I will trust; my buckler, and the horn of my salvation, and my high tower.”
Psalm 18:2

What time I am afraid, I will trust in thee.  In God I will praise His word, 
in God I have put my trust; I will not fear what flesh can do unto me.”
Psalm 56:3,4

You will keep in perfect peace those whose minds are steadfast, 
 because they trust in you. 
Trust in the LORD forever, 
for the LORD, the LORD Himself, is the Rock eternal
.”
Isaiah 26:3,4

Fear not, for I am with you.  Do not be dismayed.  I am your God.  
I will strengthen you; I will help you;
I will uphold you with My victorious right hand.
Isaiah 41:10

Give all your worries and cares to Him because He cares for you.
1 Peter 5:7

Do not be anxious about anything, but in every situation, by prayer and petition, with thanksgiving, present your requests to God.  And the peace of God, which transcends all understanding, will guard your hearts and your minds in Christ Jesus.”
Philippians 4:6-7

 Amen.


March 28, 2012

Step One - Success!


Once again, I am (practically) speechless!  We went back to MD Anderson today for the results of my bone marrow biopsy and to discuss the next step.  “Flow cytometric immunophenotyping of the bone marrow aspirate is negative for minimal residual chronic lymphocytic leukemia….”  In a nutshell, the Campath WORKED in knocking my leukemia down to nothing in one round!  Perhaps that is why I was so sick at the beginning.  It wasn’t just working at the peripheral level; it was busy working at the cellular level.

So what does this mean?  The transplant team will now contact M-47 in Europe to determine his schedule and availability for donating.  Once that is arranged, they will set the date for my transplant.  Until then, I can give my body a rest from Campath and Neupogen.  If M-47 is planning a lengthy vacation or something, we might have to revisit that decision.  For now, I am still immuno-compromised and it was emphatically communicated that I must behave! 

Dr. Shah said that I continue to be an anomaly.  Everything about my disease has been unique.  It is extremely rare for one round of treatment to knock the 80% diseased marrow down to 0.  This is a direct answer to prayer!  I am doubly blessed because this allows us to maintain a full arsenal of weapons to wage war against the leukemia if or when it relapses.  Most folks have to utilize many of their chemo darts just to get into remission.  And the less my body is worn down by drugs, the better my chance of transplant success. 

The question has been posed as to why I still need a transplant if my leukemia was knocked out.  The answer goes back to my 17p deletion, and other negative prognostic factors.  While I am in remission now, it won’t last for long.  So for a longer-term fix, the transplant is the only answer.

Once the date is set, the ten days prior to transplant will be spent in the hospital receiving the conditioning regimen (also referred to as "killer chemo").  Dr. Shah has decided on FBR.  I wrote about the various options months ago.  As a reminder, FBR stands for Fludarabine, Bendamustine (also known as Treanda), and Rituximab.  Even though there are some horrid side effects, mostly for the first two, I may not lose my hair after all!  And I was already prepared!!  :)  Good thing Paul didn’t shave his head too soon!

I know it sounds funny to be this giddy about a soon approaching transplant.  But today felt like a confirming word from the Lord that everything is going to be fine.  We are wrapped in His loving arms as He holds us up, holds us together.  Emotions have traveled up and down and will certainly continue.  But to have such a miraculous answer to prayer is simply that…a miracle.  As I said when my perfect match was found, we pray expectantly and are then surprised when it happens! 

Thank you for your faithful prayers!  While we understand that this is still just the first step, He is paving the way before us, and we trust Him to carry us through.


March 27, 2012

Good News/Bad News


Many times over the years, I’ve heard Christians say that the Good News is only good because the bad news is so bad!  Simple, yet profound.

Throughout my CLL journey, I have seen many correlations between the physical and the spiritual.  This concept is no exception.  Without having received the bad news that I have the most aggressive type of CLL, the good news that a stem cell transplant could provide a second lease on life would not have been pertinent. 

If we were not sinners permanently separated from God with no hope of accessing Him on our own, the good news of salvation through Jesus would be a waste of time. 

This righteousness is given through faith in Jesus Christ to all who believe.
There is no difference between Jew and Gentile, for all have sinned and fall
short of the glory of God, and all are justified freely by his grace through the redemption 
that came by Christ Jesus.  God presented Christ as a sacrifice of atonement, 
through the shedding of his blood—to be received by faith.”
Romans 3:22-25

As it is written: "There is no one righteous, not even one.
Romans 3:10

Nor is there salvation in any other, for there is no other name under heaven 
given among men by which we must be saved.”
Acts 4:12

For it is by grace you have been saved, through faith—and this is not from yourselves, 
it is the gift of God— not by works, so that no one can boast.
Ephesians 2:8-9

Jesus said to him, ‘I am the way, the truth, and the life. 
No one comes to the Father except through Me.’”
John 14:6

I have been reading several books by Robert Whitlow.  I am currently reading The List.  A young attorney (read the book for background:) is being drawn to the Lord while being drawn away by an unseen evil.  He had been reared in a home that “went to church” some.  But he came to realize that knowing stuff about God is not the same as having a personal relationship with the God of all. 

It equates to my transplant.  I can study and learn all about allogeneic stem cell transplants, but until I actually experience one, it will just be head knowledge.  The only way that the transplant can save my life is to have one.  Just reading about it won’t work. 

Yesterday, we went back to MD Anderson for my blood work, bone marrow biopsy, and to meet with the leukemia team.  We didn’t learn much other than whatever decision is made Wednesday regarding the timing of my transplant, I should expect to continue taking the Campath until the details revolving the transplant are complete.  That way I won’t lose ground.  Tomorrow we will find out the details.

I also learned that I am, indeed, still very immuno-compromised and need to be a good girl.  Even though the Neupogen increases my neutrophil count, my T-cells are being hammered by the Campath and I am at risk for infection.  So I will need to adhere a bit more strictly to the rules.  :/

Compared to the Good News of salvation, there are no guarantees with the transplant.  I am so thankful that with God, there are.

My sheep listen to my voice; I know them, and they follow me.  
I give them eternal life, and they shall never perish; no one will snatch 
them out of my hand.  My Father, who has given them to me, is greater than all;
no one can snatch them out of my Father’s hand.  I and the Father are one.
John 10:27-30

In all these things we are more than conquerors through Him who loved us.  
For I am convinced that neither death nor life, neither angels nor demons, 
neither the present nor the future, nor any powers, neither height nor depth,
nor anything else in all creation, will be able to separate us from the love of God
that is in Christ Jesus our Lord.
Romans 8:37-39

Think on these things.  Selah.




March 23, 2012

Fork in the Road


Today was the end of the first leg of my journey towards transplant, and we can see the upcoming fork in the road.  Monday, we head back to MD Anderson for a bone marrow biopsy and meeting with Dr. O’Brien and the CLL team.  Wednesday, we’ll get the results of the biopsy and meet with Dr. Shah and the transplant team.  At that point, the decision will be made whether to continue on the Campath road for another round or to take the path directly to transplant.  It all depends on the level of disease left in my marrow.  Having been near 80% diseased marrow, Paul’s bet is on another round of Campath.  I’m ready to move on.  But this part is not our decision.

The past week or so could be classified as “side effect of the day.”  Some days I would have a rash.  Others I would have some light nausea.  Many brought increased fatigue, intestinal distress, or a return of the headaches.  Some weren’t bad at all.  And none have been as bad as the first week!  So for that I am immensely thankful.

I have taken time to read.  (I’m on my third book in four weeks.)  I have talked and Skyped with my kids and grandkids.  I have spent quiet times with my sweetheart.  I had a wonderful visit from a dear friend.  (Love you, Cheryl!)  I have enjoyed several mornings with my cousins, Al & Bonnie, who live around the corner from where I get my shots.  And I even felt well enough last night for my mom and Maxine, her neighbor and buddy, to come over for dinner and a game of cards.  I was pretty pooped out by the end of the evening, but it was a nice tired.

I have come to care deeply for the team at the good doctor’s office.  They are not only efficient but also very compassionate and caring.  It was a little sad leaving today not knowing if I’d be back anytime soon.  I’m sure that the same level of connection will happen with my transplant team on MD Anderson’s 11th floor.  Prayerfully, a year from now, these will be memories of a time when….  Memories that I will never forget.  Memories that will mold my future.


March 14, 2012

Steady As She Goes


This is a phrase indicating instruction from the captain to the helmsman of a ship to keep the ship heading steadily on the same course regardless of gusts of wind or cross currents.  That sounds like a fairly accurate description of where I am right now.  I have been steadily receiving my Campath injections for almost three weeks.  A sudden gust at the beginning of week two caused the captain to introduce Neupogen to help keep me on course without sinking the ship.  So far, so good.  My counts continue to climb back into the normal range.

The early onset of thunderous side effects has calmed.  The few that remain or that have recently appeared do not rock the boat like their predecessors.  The headaches are minimal, and I have had no further fever, chills or rigors.  Fatigue is still my daily companion accompanied by increased body/bone ache (due in part to the Neupogen).  The newest squall is a pesky rash, looking more akin to hives, which appears on my face and neck every evening.  Last night was the worst.  After dinner and visiting with Paul and his son Chris, I looked like I had the mumps.   I decided to take an oatmeal bath and soak my face!  I followed that with Aveno lotion, Cortizone cream, two Benedryls, and finally Benedryl gel, which brought the relief needed to sleep.  I should market the mix because this morning my skin looked amazing!  :)  But the rash will most likely return again this evening.  It’s the Campath.

I have been able to wrap my head around most everything we have learned and the choices that have been made on my behalf, but I have to admit that I have not been able to totally understand the relationship between Campath and Neupogen. The goal of Campath is to knock down the leukemia and get me into remission. The Neupogen’s role is to salvage my neutrophils in order to keep my ship from sinking while the hull is being cleaned. My concern was whether or not the Campath could be as effective in its destroying if the Neupogen was rebuilding at the same time. I also wasn’t certain if my increased numbers meant that I was no longer immunocompromised. While I trust the doctors’ judgment, I just needed to understand. Dr. O’Brien’s PA, Jill, emailed a response to my question. “The Campath targets the lymphocytes, and the Neupogen builds the neutrophils, so unrelated to each other (even though they both are part of the white blood cells). Yes, you are still very immunocompromised because of the Campath. More for viral-type illnesses which is where the lymphocytes are important.”

OK.  Good enough.  While the Campath does lower all my numbers, not just my lymphocytes, it’s an answer I can wrap my head around.  

So we will continue sailing through another week of Campath and look forward to my bone marrow biopsy on March 26 to see what kind of damage it did there.  No worries.  We want it to have done some damage!  If it has successfully knocked down the bad guys, we will get ready to proceed to transplant.  If it’s working but still has more to do, then we will hoist the sail for another four weeks.  Whatever the case, the waters are less choppy than before and we are trusting Him to see us through.

Then they cried out to the LORD in their trouble, 
and He brought them out of their distress.  
He stilled the storm to a whisper; the waves of the sea were hushed.  
They were glad when it grew calm, and He guided them to their desired haven.  
Let them give thanks to the LORD for His unfailing love and His wonderful deeds for men.
Psalm 107: 28-31


March 9, 2012

A Complete 180


For all of you who prefer Paul’s shorter posts, I am providing one today.  :)  By God’s grace and your faithful prayers, I feel a hundred times better than I did last week.  I have not had any further fevers, chills, rigors, or nausea, and the headaches have been held to a minimum.  I’m still tired, and I still have to behave :/, still need my naps, still have to take all my meds, still can’t go a lot of places or be around little ones, but this is the best I’ve felt since before I started the treatments.

My numbers have come up steadily this week (from 0 to 1 to 2).  And so far, I have not had a reaction to the Neupogen.

God is good.  He was good last week too, even though I felt so bad, because He carried me through.   It gave me an opportunity to see just a little of what the transplant process and side effects might be like.  He is preparing me for what is to come.  Thank you, God, for this week’s respite!

"Praise the Lord; praise God our Savior!  For each day He carries us in His arms."
Psalm 68:19 NLT

March 7, 2012

Back on Track


Because my counts were too low for me to get a Campath injection on Monday, the office of the good doctor conferred with MD Anderson to decide whether or not to re-start my ramp up doses (since today was 7 days since my last injection) or to continue at 30 mg or a reduced dosage.  The decision to add Neupogen, which helps rebuild the neutrophils, also came into play.

Late yesterday, we learned that we would resume the 30 mg injections and add a Neupogen injection every time I get the Campath or until my neutrophil numbers have risen to the desired level.  Much of this morning was spent reviewing the insurance vs. out-of-pocket expenses for the pricey Neupogen.  We finally helped them realize that by the time we pay for the Campath, my deductible will have been met and it won’t really matter.  The Neupogen will be covered.  Just give me the shot.

My numbers had gone up a little.  But that little amount (WBC up from .76 to 1.38 and Neutrophils up from .54 to .97) was enough for me to get my Campath and wait until Friday to start the Neupogen.  I did have to have the IV Benedryl today :( but that should be the last time.  It hurt more today, and I have a bruise.  Friday, I will take my Benedryl by mouth on my way to the office.  So we are back on track.  

So in a nutshell, perhaps a big nutshell but nutshell nonetheless, the Campath does such a good job killing my white blood cells that I will have to take Neupogen injections every time Campath knocks them down.  I have been taking Tramadol to counter the bone and body aches.  Since the main side effect of Neopogen is more intense bone and body aches (because it pushes my bone marrow factory to work harder), I am hoping that my Tramadol works overtime.  Because my immune system is in the dirt, I will continue taking Valcyte to guard against viral infections and Bactrim DS to ward off bacterial infections.  Since most all of these, especially the Campath, cause severe headaches, I will continue taking Flexeril to help me relax and Maxalt to fight the ones that just don’t want to go away.  When all of this makes me nauseated, I will rely on the Phenergan.  Then, of course, I can take all the Tylenol and Benedryl I would like to cover the itching, sleeplessness, rash, and any other pain that hasn’t been covered.  I think I got them all.

Where is my card table?!



March 5, 2012

Unexpected News! Down for the Count


After the rigors of last week followed by a less intense weekend, Paul and I made our way back to the good doctor’s office to start week two.  Or so we thought.  We were curious to find out how much this first week of Campath affected my counts.  The answer…drastically!  In fact, my white blood count is currently just over 0 at .76.  Yes, you read that correctly.  My neutrophil count (which are the white blood cells that fight infection) is just over 0 at .54.  We were all in shock!  My disease has been a bit of an anomaly since the start.  This only adds to it.

So what does that mean?  Well, first, it means that I didn’t get a shot today.  They couldn’t take the chance of infection.  Next, it means that I am “down for the count”…literally!  I now have no immune system.  I will be susceptible to viral, bacterial, as well as fungal infections.   That means no fresh uncooked produce, no medium rare steaks, no grocery stores or movie theaters, no gardening, no kids, no kissing, no nothing.  And if I do go somewhere or if someone comes over, I will be donning a mask.  (We have tried to find pretty ones but to little avail.) 

I had already planned on asking the good doctor how it is that a little lady, now weighing in under 120, and a manly man, weighing 220 pounds or more, can handle the same 30mg of Campath?  He thought that was quite an astute question, thank you!  :)  I don’t quite remember the entire answer other than the dosages are calculated generically, like Tylenol, etc., rather than by weight.  But it does give way to thought.  So he is going to contact Dr. O’Brien at MD Anderson and discuss the option of a reduced dosage.  We will know Wednesday when we go back to have my numbers checked again.

You would think that at this point they could just move on to transplant.  But the counts in my peripheral blood do not necessarily equate with the counts in my bone marrow.  They will discover that when they do my next bone marrow biopsy. 

We assume (which is not something we like to do, you know) that my counts will go up a little between today and Wednesday since I did not get another injection.  Other than waking up with another headache, which has since mellowed out, I feel better today.  Still very tired and not especially receptive to food, but better nonetheless.  For that I am very thankful.  I have heard of your faithful prayers and appreciate you all so much!

What else might this mean?  We will probably not need the second round.  That would probably put the transplant in April rather than May.  Deep breath.  

I never said that this was going to be a boring ride.  


March 4, 2012

Moment by Moment


Wow!  What a week!  I must confess that this was not what I expected from my ramp-up week of Campath.  As of my last post, the proverbial truck had run me over.  Since then, it has backed up and plowed me down a few more times.  Thursday evening was pretty bad, and Friday was horrible.  I think I’d rather go back to the chills and fever!

After trying everything to manage the headache and nausea, I finally called my nurse to see if we could try a different drug.  I think I mentioned that my original anti-nausea drug (Granisetron, or Kytril for short) was not only not helping my nausea, I think it was aggravating the headache problem.  When I talked to my nurse, she assured me that there were several other options that shouldn’t cause headaches.  She called in Phenergan, both varieties, if you know what I mean.  One variety works faster and is less likely to come back up.  :/  Good times.  The good doctor also had her call in Flexeril, a muscle relaxer, to hopefully help relieve some of the pain.

Because things had gone from bad to worse, Paul was able to get permission to leave work midday Friday, go pick up my new meds, and be home with me for the rest of the day.  Have I mentioned how wonderful he is lately?!  :)

The Phenergan worked well.  The Flexeril decreased the pain level by about 40-45%, which was huge at that point.  We continued with all my other meds trying to find a balance of what would work.  Fortunately, I slept Friday night.

Unfortunately, Saturday’s sunrise greeted me with yet another headache.  I took my Maxalt (migraine med) and another Flexeril, along with my regular mix.   You’d think I would have been comatose by then with all these drugs in me.  Within forty-five minutes, I was able to eat a small amount of oatmeal and 2 ozs of a mango protein drink.  Ick.  As the day went on, I continued on my regular 3/day Tramadol (pain killer), my two antibiotics, Tylenol and Flexeril whenever I’d feel the headache inching back, and whatever else I’m taking.  By late afternoon, Paul and I actually went for a walk around the pond!  Success!!  Maxalt again at 9pm for the headache that just would not stay away and another pretty good night’s sleep…until the sun rose with yet another headache!  This time I hit it with Maxalt and a little more sleep.  I wanted to try to go to church.  Work with me here!

A few weeks ago, my sweet friend from church, Dian, invited me and her dear friend, Jan, who went through a stem cell transplant this past year, over for lunch and a time of sharing.  Dian’s husband is now in his third bout with cancer.  (Please keep John & Dian in your prayers.)  Jan is successfully on the other side of a stem cell transplant having battled an acute form of leukemia.  We spent four hours together sharing each others’ journeys, asking questions, enjoying a lovely lunch, and ending in the wonderful world of girl-talk, about everything from our kids and grandkids to face cream, makeup, and tattooed eyebrows. :)  The reason I mention this here (I always come full circle if you just hang in there with me) is at one point of the conversation Dian and Jan laughingly recalled how they had to set up a card table in Jan’s post-hospital apartment to manage and organize all the medications.  At that point, I could not imagine needing an entire card table for pill bottles.  Well, I can now.

So back to this morning.  My Maxalt and my body decided to work together and by the time I woke up again, the headache was gone.  OK.  I’ll try making coffee.  Done.  How about wetting my hair and washing my face?  Done.  How about sitting down for a minute.  OK.  Fluff the clothes in the dryer and fold them.  Done.  (If you’re wondering where Paul was at this time, he was still asleep.  Bless his heart.  He is working so hard at the caretaker thing, on top of all his regular responsibilities, that I couldn’t bear to wake him until I was sure.)  So I was being quiet.  Yes, me.  I can be quiet.  So let’s try putting on some clothes and makeup.  OK, but how about sitting on the side of the tub when possible.  Wow, I might be able to do this.  Guess I’ll wake up Paul since I only have hair left to do.  So, after utilizing my new sitting position for fixing my hair, and eating a bowl of oatmeal, I’m ready to go.  I haven’t accomplished that much in any one DAY this past week. 

What a blessing to be welcomed by His people and warmed by the worship of our God.  Thank you, God, for giving me the strength to be with this body of believers who lift You up in praise and hold me up in prayer. 

God often speaks to me through music.  I found it almost humorous that the first song was “I’ll Fly Away”!!  Indeed, I will.  But not this week.  :)  A new song was also introduced.  The first verse started with “Slow me down, oh Lord, slow me down.”  Paul and I just looked at each other and smiled because, as I have written about before, my life had been at a break-neck pace for years.  It seems that when He wants to get my attention I get some weird sickness, which slows me down.  Well, Lord.  This is about as slow as I’ve ever been.  The second verse started with “Clear my mind” and the third with “Wake my soul.”  I’ll take both please.

A nap was necessary immediately after returning from church.  I was able to eat, and now I have been able to write.  This has been a good day.  Tomorrow we start over again.   Please pray that we don’t have a repeat of this week.  If we do, please pray for grace and endurance.  I know it’s only for a season.   We have determined to travel this journey one day at a time.  This week has taught us to take it one moment at time.  Moment by moment, He carries us through.

Moment by moment I’m kept in His love;
Moment by moment I’ve life from above;
Looking to Jesus till glory doth shine;
Moment by moment, O Lord, I am Thine.

Never a trial that He is not there,
Never a burden that He doth not bear,
Never a sorrow that He doth not share,
Moment by moment, I’m under His care.

Never a heartache, and never a groan,
Never a teardrop, and never a moan;
Never a danger but there on the throne,
Moment by moment He thinks of His own.

Never a weakness that He doth not feel,
Never a sickness that He cannot heal;
Moment by moment, in woe or in weal,
Jesus my Savior abides with me still.


March 1, 2012

Run Over by a Truck!


Considering that we named this blog, Our Journey, I thought that this was a perfect analogy of how I feel.  I have been told before that I tend toward optimism and believing the best.  In that vein, I was convinced that I was going to ride out this first leg without a glitch.  Oh, well, so much for that.

The first day wasn’t too bad.  A little nausea (that I didn’t take the pill for) followed later in the day by light itchiness that made it difficult to get to sleep.  But really no big deal.  Day 2 was when my left arm started hurting, but luckily neither my right arm nor my leg had the same response post injection.  By Tuesday evening, I started having chills and rigors and running a low-grade temperature.  You just can’t make it stop.  I tried deep breathing and willing it away, but it has to run its course.  Day 3 I still had a low-grade temp but everything else went well at the doctor’s office.  By early afternoon, the chills and rigors returned.  Then last evening the chills started again, the nausea returned (and I did take my pill), my head hurt, and my temperature went up to 100.8 and stayed up until sometime after I went to sleep.  I know that doesn’t sound very high, but we’re supposed to call when it gets to 100.5.  So I did.  The on-call doctor said to take Tylenol.  :/  I called my nurse this morning so she could inform the good doctor.

Which brings us to today.  Since I didn’t have to go in for an injection today, I had planned on going grocery shopping and sprucing up around the house a bit.  Yeah, that didn’t happen.  I feel like I’ve been run over by a truck!  Because of all the sweats from last night, I needed to shower again this morning.  It’s really weird to wish that the Campath would make my hair fall out just so I wouldn’t have to wash, dry, and attempt to fix it!  Had to pull a chair into the bathroom to get through it.  I won’t have the blessing of no hair to wash until I get to MD Anderson and take the really hard stuff.  Funny how your perspective changes.

I’ve also lost more weight.  Not surprising because everything tastes horrible.  I can usually out-eat Paul, but not now.  So I am now sipping on a Boost Plus.  Later, I am going to attempt to make chicken and dumplings with the rest of the rotisserie chicken Paul brought home last night.  Here’s hoping.  (He also brought home my favorite flowers…daisies!  What a dear!) 

The encouraging thing is that from all we’ve read, the side effects (other than the suppressed immune system) should balance out once my body gets acclimated to the drug.  I am hoping that’s the case.

I know that it could be SO much worse!  The sub-q injections have much milder side effects than the IV version, so for that I am very thankful.  It’s also almost funny to read about all the various side effects of the drugs given to overcome the other drugs’ side effects.  My anti-nausea pill can cause headaches, difficulty sleeping, dizziness, bowel issues, etc., etc, etc.  The Valcyte can cause back pain, bowel issues, headache, nausea, trouble sleeping….  The Bactrim DS most common adverse effects are "gastrointestinal disturbances" (nausea, vomiting, anorexia), and skin reactions.  And that doesn’t even include the Campath!  You wonder how folks live through the remedy!!  But as a song in the last episode of GLEE exclaimed, “What Doesn’t Kill You Makes You Stronger!”  :)

In your prayers, please add our dear friends John & Dian Sustek.  John has battled cancer twice and this week has entered a third round.  It’s been a long difficult week for them.  Please keep these sweet, Godly people in your prayers.